Differential prooxidative effect of adult and fetal hemoglobin
نویسندگان
چکیده
منابع مشابه
Aggregation of adult and fetal hemoglobin by ingested nitrate anions
The ingested nitrates sourced from tap water, food, chemicals and pharmaceuticals areconverted to nitrites in the body surfaces by bacteria and then, the nitrite ions can lead thestructural changing in hemoglobin. In the present work, aggregation of the purified hemoglobinin adult (HbA) and in fetus or newborn (HbF) in the presence of nitrite ions were studied.Hemoglobin aggregation was perform...
متن کاملaggregation of adult and fetal hemoglobin by ingested nitrate anions
the ingested nitrates sourced from tap water, food, chemicals and pharmaceuticals areconverted to nitrites in the body surfaces by bacteria and then, the nitrite ions can lead thestructural changing in hemoglobin. in the present work, aggregation of the purified hemoglobinin adult (hba) and in fetus or newborn (hbf) in the presence of nitrite ions were studied.hemoglobin aggregation was perform...
متن کاملThe switch from fetal to adult hemoglobin.
The fetal-to-adult hemoglobin switch and silencing of fetal hemoglobin (HbF) have been areas of long-standing interest among hematologists, given the fact that clinical induction of HbF production holds tremendous promise to ameliorate the clinical symptoms of sickle cell disease (SCD) and β-thalassemia. In this article, we discuss historic attempts to induce HbF that have resulted in some ther...
متن کاملFetal hemoglobin (HbF) synthesis in baboons, Papio cynocephalus. Analysis of fetal and adult hemoglobin synthesis during fetal development.
Fetal hemoglobin (HbF) and adult hemoglobin (HbA) synthesis was studied in fetal baboons, Papio cynocephalus, to determine the normal pattern of hemoglobin production during fetal development. Fetuses ranging from 53 to 180 days gestation (term gestation 184 days) were used. Erythroid cells were incubated with 3H-L-leucine, and the rates of globin chain synthesis and the distribution of radioac...
متن کاملAggregation of adult and fetal hemoglobin by ingested nitrate anions
The ingested nitrates sourced from tap water, food, chemicals and pharmaceuticals are converted to nitrites in the body surfaces by bacteria and then, the nitrite ions can lead the structural changing in hemoglobin. In the present work, aggregation of the purified hemoglobin in adult (HbA) and in fetus or newborn (HbF) in the presence of nitrite ions were studied. Hemoglobin aggregation was per...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1986
ISSN: 0014-5793
DOI: 10.1016/0014-5793(86)80278-2